Tag Archives: National Medal of Science

Jews of the Week: Mildred Cohn and Gerty Cori

Great Women in Biochemistry 

Mildred Cohn (1913-2009) was born in New York to Jewish-Russian immigrants. Her father was a rabbi and Cohn grew up in a religious, Yiddish-speaking home, though one which also prioritized secular education and the arts. Cohn graduated high school by the age of 14 and got her Bachelor’s degree in biochemistry at 18, followed by her Master’s from Columbia University. Unable to afford any further schooling, Cohn got a job researching for the National Advisory Committee for Aeronautics (NACA), which would later become NASA. She was the only woman among seventy men, and was told she shouldn’t expect any promotions. Two years later, she had enough money to return to school, pursuing her PhD at Columbia under recent Nobel Prize-winner Harold Urey. Cohn focused her work on carbon and oxygen isotopes. From there, she moved on to Washington University to do research on metabolism using sulfur isotopes. Later, she switched to using nuclear magnetic resonance and made a huge breakthrough in 1958 when she was able to visualize ATP, the central energy molecule that powers human cells and essentially all living things. Cohn discovered much of what we know about ATP and how it works. All in all, she wrote 160 scientific papers and won numerous awards, including the National Medal of Science (awarded to her by President Reagan). She was the first female editor of the Journal of Biological Chemistry and the first female president of the American Society for Biochemistry and Molecular Biology. In 2009 she was inducted in the National Women’s Hall of Fame. Cohn was married to renowned Jewish physicist Henry Primakoff. Many of her ATP discoveries came while she was working at the lab of another great Jewish scientist, Gerty Cori.

Gerty Theresa Radnitz Cori (1896-1957) was born in Prague. Her father was a chemist who had invented a new way of refining sugar. At 16, Cori decided to become a doctor, but found that she was missing nearly all the prerequisites. So, in one year she took eighteen years-worth of courses in Latin, science, and math. Cori passed her entrance exam and was among the first women ever to be admitted to Prague’s medical school. After graduating, she worked at a children’s hospital and also did research on blood disorders, the thyroid gland, and the body’s ability to regular temperature. Due to persistent food shortages and rising anti-Semitism after World War I, Cori and her husband (also a doctor and scientist) left Prague and moved to New York. The couple did research together at what is now the Roswell Park Cancer Institute in Buffalo, focusing on glucose metabolism. Cori published 11 papers of her own, and another 50 together with her husband. By 1929, the Coris had figured out how the body metabolized glucose in the absence of oxygen, a process now known as the Cori Cycle. For this, they won a Nobel Prize in 1947. This made Cori the first American woman to win a Nobel Prize (and only the third woman overall), as well as the first woman ever to win a Nobel Prize in Medicine. In 1931, the couple took over a lab at Washington University (with Cori being paid one-tenth her husband’s salary). Here they made many more vital scientific discoveries, and mentored a new generation of scientists—six of which went on to win Nobel Prizes of their own. For this reason, their lab was deemed a National Historic Landmark in 2004. Like Mildred Cohn, Gerty Cori won countless awards and was inducted into the National Women’s Hall of Fame. There are craters on the Moon and on Venus named after her, as well as a commemorative US stamp. After battling the disease for a decade, Cori succumbed to bone cancer, likely caused by her extensive work with X-rays.

Words of the Week

In the next world, they will not ask me: “Why were you not Moses?” They will ask me: “Why were you not Zusha?”
– Rabbi Zusha of Anipoli (1718-1800)

Jew of the Week: Steven Weinberg

Architect of the Standard Model of Physics

Steven Weinberg

Steven Weinberg (b. 1933) was born in New York to Jewish parents of Romanian and German heritage. He studied at the Bronx High School of Science, then did his undergraduate studies in physics at Cornell. After a brief stint at the Niels Bohr Institute in Denmark, he earned his PhD at Princeton in 1957. Weinberg first did research at Columbia University, then became a professor at UC Berkeley. While there, he started writing one of his most famous books, The Quantum Theory of Fields, as well as the popular textbook Gravitation and Cosmology. In 1966, Weinberg moved back east to teach at Harvard. The following year, as a visiting professor at MIT, he published his new model unifying electromagnetism and the nuclear forces. Part of this was proposing the existence of the Higgs boson (which was finally discovered in 2012). Weinberg’s model built on the work of his former high school classmate and fellow Jewish physicist, Sheldon Glashow. The two shared the 1979 Nobel Prize in Physics for their work (together with Pakistani physicist Abdus Salam). Over the years, Weinberg did research on—and greatly furthered our understanding of—gravity and cosmology, quantum physics and string theory, pions, leptons, and supersymmetry. His work has expanded nearly every aspect of modern physics and is among the most renowned scientists in the world. Weinberg has testified before Congress as an expert witness, and has written many popular articles and science books, among them The First Three Minutes and To Explain the World: The Discovery of Modern Science. He has been awarded 11 honourary degrees together with a long list of awards including the National Medal of Science. Weinberg is also a staunch supporter of Israel and has refused to speak at universities that boycott the Jewish State. Today, as he nears his 87th birthday, he continues to write and teach physics at the University of Texas at Austin.

Words of the Week

Given the history of the attacks on Israel and the oppressiveness and aggressiveness of other countries in the Middle East and elsewhere, boycotting Israel indicates a moral blindness for which it is hard to find any explanation other than antisemitism.
– Steven Weinberg

Jew of the Week: Gertrude Elion

The Woman Who Saved Millions of Lives

Gertrude Elion

Gertrude Belle Elion (1918-1999) was born in New York to Lithuanian- and Polish-Jewish immigrants. She excelled at school, and when her grandfather passed away from cancer, was determined to find the cure. She went on to volunteer as an assistant in a chemistry lab, and was eventually hired for just $20 a week. She used that money to pay for school, earning her Master’s in chemistry in 1941. Unfortunately, Elion was rejected for all fellowships and post-graduate positions because of her gender. Instead, she went to work for a supermarket, testing food quality. From there, she got a job as an assistant in a New York pharmacology lab (now owned by GlaxoSmithKline). Working under the supervision of George Hitchings, she developed two new anti-cancer drugs by 1950. Elion continued to work at the lab, and eventually became the head of its Experimental Therapy department. Despite never formally earning a Ph.D, she was a professor of pharmacology at Duke University between 1971 and 1999. Among the drugs that Elion developed are Purinethol (the first leukemia medication), Daraprim (to treat malaria), and Acyclovir (the first and most common antiviral medication, used to treat herpes, chicken pox, and shingles). Azathioprine, a drug to prevent organ transplant rejection which Elion discovered in 1963, has since been used to ensure successful kidney transplants for over 500,000 people. She also developed drugs to treat meningitis, gout, urinary, and respiratory infections. While Elion officially retired from drug-making in 1983, she was inspired to continue working due to the then-recent outbreak of HIV/AIDS. She continued working full time until the successful release of AZT, the first drug to treat AIDS. For all of this tremendous work, which saved the lives of countless thousands, Elion was awarded the Nobel Prize in Medicine in 1988. She received a National Medal of Science in 1991, and in that same year became the first woman ever inducted into the National Inventors Hall of Fame. (Elion holds 45 patents.) She finally received an honourary Ph.D from New York University in 1989, and another doctorate from Harvard when she was 80 years old. She is recognized as one of the greatest pharmacologists and biochemists of all time.

Red Sea or Reed Sea: Where is Mount Sinai?

Words of the Week

If you wait until you find the meaning of life, will there be enough life left to live meaningfully?

– Rabbi Menachem Mendel Schneersonthe Lubavitcher Rebbe